About this property

Prime Downtown Guelph Office Sublease at 45 Wyndham St N - an exceptional opportunity for medical professionals, health practitioners, legal, financial, or professional service firms seeking a prestigious and highly visible street-level or upper-level address in the heart of Guelph's vibrant downtown core. This well-maintained commercial space is perfectly suited for physicians, dentists, physiotherapists, chiropractors, counsellors, or allied health providers looking to establish or expand their practice in a centrally located, client-friendly setting. Situated at the prominent intersection of Wyndham St N and Quebec St, the property benefits from outstanding exposure to heavy daily foot and vehicle traffic along Guelph's premier commercial corridor. Zoned C3, the space accommodates a wide range of professional and medical uses within an Official Plan Mixed-Use designation. Transit is steps away with a major transit station area and street-level bus stops within a one-minute walk, ensuring easy access for patients, clients, and staff alike. Downtown Guelph offers an unparalleled amenity-rich environment with restaurants, cafes, retail shops, banking, and professional services all within walking distance. Ample nearby parking is available via the West Parkade and on-street metered options. The surrounding neighbourhood features the Sleeman Centre, public library, and a thriving arts and culture district. Flexible sublease terms available. Ideal for practitioners who value accessibility, walkability, and a professional downtown presence.

Features & finishes

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Air Conditioning

Basement

Property details

MLS® Number	X12885204
Status	Active
Listing Type	For Lease
Property Type	Commercial
Interior Size	1,203 sq ft
Beds / Baths	0 bed · 0 bath
Neighbourhood	Downtown
City	Guelph
Postal Code	N1H 4E4
Province	ON
Listed Date	March 15, 2026
Days on Market	144
Price per Sq Ft	$2
Brokerage	EXP REALTY